- claim_text
The Blue Brain CCFv3 augmented atlas extends Allen's CCFv3 to fully annotate olfactory bulb, cerebellum, medulla and central nervous system regions and aligns 734 Nissl-stained brains to produce an averaged 10-µm Nissl template — the registration substrate on which cell-type counts and projection-target labels in mouse-cortex E→E synthesis depend.
- raw_fields
{
"n": 734,
"doi": "10.1162/imag_a_00565",
"claim": "The Blue Brain CCFv3 augmented atlas extends Allen's CCFv3 to fully annotate olfactory bulb, cerebellum, medulla and central nervous system regions and aligns 734 Nissl-stained brains to produce an averaged 10-µm Nissl template — the registration substrate on which cell-type counts and projection-target labels in mouse-cortex E→E synthesis depend.",
"cite_key": "Piluso2025",
"evidence": "Atlas extension covering previously missing regions; 734 brains aligned for averaged Nissl template; first in silico whole-CNS cell-distribution model.",
"effect_size": "734 Nissl brains aligned; 10 µm averaged template",
"text_access": "fulltext",
"study_system": "Whole mouse brain atlas (extended CCFv3)",
"argument_role": "supporting",
"replication_status": "atlas-resource",
"claim_source_sentence": "we developed the Blue Brain Project (BBP) CCFv3 augmented atlas (CCFv3BBP), which includes a fully annotated mouse brain and an improved Nissl-stained reference volume aligned with the CCFv3BBP. This enhanced atlas also features the central nervous system annotation.",
"source_provenance_status": "ok",
"replication_evidence_dois": [],
"effect_size_source_sentence": "we aligned 734 Nissl-stained brains to generate an average Nissl template at 10 µm resolution."
}- source_refs
[
"paper:paper-3cf435c26092"
]
- source_span
we developed the Blue Brain Project (BBP) CCFv3 augmented atlas (CCFv3BBP), which includes a fully annotated mouse brain and an improved Nissl-stained reference volume aligned with the CCFv3BBP. This enhanced atlas also features the central nervous system annotation.
- evidence_refs
[
{
"ref": "paper:paper-3cf435c26092"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}