Details

scope
mouse, barrel cortex, optogenetics + in vivo recording
claim_text
A disinhibitory VIP→SST→pyramidal circuit mediates motor cortex integration in somatosensory cortex during whisking
section_id
section_08_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
effect_size
increased VIP firing, decreased SST firing during whisking
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-08
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
S1-projecting vM1 pyramidal neurons strongly recruited vasointestinal peptide (VIP)-expressing GABAergic interneurons
study_system
mouse, barrel cortex, optogenetics + in vivo recording
section_title
In Vivo Dynamics and Behavioural Correlates
evidence_summary
VIP interneurons preferentially inhibited SST interneurons; VIP activity increased and SST activity decreased during whisking dependent on vM1 activity
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-08
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1038/nn.3544",
  "claim": "A disinhibitory VIP→SST→pyramidal circuit mediates motor cortex integration in somatosensory cortex during whisking",
  "evidence": "VIP interneurons preferentially inhibited SST interneurons; VIP activity increased and SST activity decreased during whisking dependent on vM1 activity",
  "effect_size": "increased VIP firing, decreased SST firing during whisking",
  "text_access": "fulltext",
  "study_system": "mouse, barrel cortex, optogenetics + in vivo recording",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "S1-projecting vM1 pyramidal neurons strongly recruited vasointestinal peptide (VIP)-expressing GABAergic interneurons",
  "replication_evidence_dois": [
    "10.1038/nature12354"
  ],
  "effect_size_source_sentence": "the activity of VIP interneurons in vivo increased and that of somatostatin interneurons decreased during whisking"
}
source_refs
[
  "paper:paper-f02f24cb44ff"
]
evidence_refs
[
  {
    "ref": "paper:paper-f02f24cb44ff"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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