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- Live5/17/2026, 4:35:28 PM
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{ "scope": "balanced spiking PFC network with facilitating recurrent synapses", "claim_text": "Highly irregular persistent activity in working memory implies a balanced-excitation/inhibition regime in which the supporting nonlinearity lies in inter-neuronal recurrent interactions; short-term synaptic facilitation on recurrent E→E synapses can implement this nonlinearity.", "raw_fields": { "n": 0, "doi": "10.1523/jneurosci.3455-12.2013", "claim": "Highly irregular persistent activity in working memory implies a balanced-excitation/inhibition regime in which the supporting nonlinearity lies in inter-neuronal recurrent interactions; short-term synaptic facilitation on recurrent E→E synapses can implement this nonlinearity.", "cite_key": "Hansel2013", "evidence": "Balanced-network theory plus spiking model with facilitating E→E synapses fits irregular persistent firing in monkey PFC oculomotor delay tasks.", "effect_size": "qualitative", "text_access": "abstract_only", "study_system": "balanced spiking PFC network with facilitating recurrent synapses", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "We show that this requires that nonlinearities underlying the persistent activity are primarily in the neuronal interactions between PFC neurons.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1126/science.1150769", "10.1038/nn.3645" ], "effect_size_source_sentence": null }, "section_id": "section_13", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json", "effect_size": "qualitative", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-13-attractor-network-models", "source_kind": "review_finding", "source_path": "evidence/section_13_evidence_package.json", "source_refs": [ "paper:paper-753d63dc018f" ], "source_span": "We show that this requires that nonlinearities underlying the persistent activity are primarily in the neuronal interactions between PFC neurons.", "study_system": "balanced spiking PFC network with facilitating recurrent synapses", "evidence_refs": [ { "ref": "paper:paper-753d63dc018f" } ], "section_title": "13. Attractor-network models — Hopfield, ring, line, bump; what each model requires of the cortical E→E matrix and what the mouse empirical record provides", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Balanced-network theory plus spiking model with facilitating E→E synapses fits irregular persistent firing in monkey PFC oculomotor delay tasks.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "independently_replicated", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-13-attractor-network-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }