Version history

{
  "scope": "rodent neocortex (review)",
  "claim_text": "Tremblay et al. (2016) reviewed evidence that VIP+ cortical interneurons co-express subsidiary markers in distinct subpopulations: CCK in multipolar VIP cells, calretinin (CR) in irregular-spiking bipolar VIP/CR+ cells, and choline acetyltransferase (ChAT) in a small VIP/ChAT bipolar subgroup.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2016.06.033",
    "claim": "Tremblay et al. (2016) reviewed evidence that VIP+ cortical interneurons co-express subsidiary markers in distinct subpopulations: CCK in multipolar VIP cells, calretinin (CR) in irregular-spiking bipolar VIP/CR+ cells, and choline acetyltransferase (ChAT) in a small VIP/ChAT bipolar subgroup.",
    "title": null,
    "cite_key": "Tremblay2016",
    "evidence": "VIP IN subpopulations: VIP/CCK multipolar (basket-like), VIP/CR bipolar (irregular spiking), VIP/ChAT (cholinergic, upper layer). Intersectional Vip-flp × CR-cre genetics confirmed VIP/CR cells enriched in irregular-spiking bipolar phenotype (He et al. 2016).",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "rodent neocortex (review)",
    "target_section": "section_11",
    "_source_cluster": "cluster_01_molecular_taxonomy",
    "replication_status": "replicated",
    "_source_cluster_index": 20,
    "claim_source_sentence": "Multipolar VIP INs include VIP INs expressing CCK and a group of L6 multipolar VIP cells with an intralaminar axon spanning laterally. Some Vip INs also express the ACh synthetizing enzyme choline acetyl transferase (ChAT). Vip CR+ INs behave differently than Vip CR- neurons in terms of the role of activity in their migration and maturation."
  },
  "section_id": "section_01",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-01-introduction",
  "source_kind": "review_finding",
  "source_path": "evidence/section_01_evidence_package.json",
  "source_refs": [
    "paper:paper-53c8505de50f"
  ],
  "source_span": "Multipolar VIP INs include VIP INs expressing CCK and a group of L6 multipolar VIP cells with an intralaminar axon spanning laterally. Some Vip INs also express the ACh synthetizing enzyme choline acetyl transferase (ChAT). Vip CR+ INs behave differently than Vip CR- neurons in terms of the role of activity in their migration and maturation.",
  "study_system": "rodent neocortex (review)",
  "evidence_refs": [
    {
      "ref": "paper:paper-53c8505de50f"
    }
  ],
  "section_title": "Introduction",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "VIP IN subpopulations: VIP/CCK multipolar (basket-like), VIP/CR bipolar (irregular spiking), VIP/ChAT (cholinergic, upper layer). Intersectional Vip-flp × CR-cre genetics confirmed VIP/CR cells enriched in irregular-spiking bipolar phenotype (He et al. 2016).",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-01-introduction",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}