Version history

{
  "scope": "mouse V1",
  "claim_text": "To obtain a more informed understanding of how vision drives plasticity during critical periods and why this influence is lost with age, we investigated the modulation of pyramidal neurons and the three major types of inhibitory neurons in primary visual cortex: dendrite-targeting SST cells, soma-targeting PV cells, and cells expressing the vasoactive intestinal peptide (VIP) 18 .",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41586-019-0963-3",
    "year": "2019",
    "claim": "To obtain a more informed understanding of how vision drives plasticity during critical periods and why this influence is lost with age, we investigated the modulation of pyramidal neurons and the three major types of inhibitory neurons in primary visual cortex: dendrite-targeting SST cells, soma-targeting PV cells, and cells expressing the vasoactive intestinal peptide (VIP) 18 .",
    "title": null,
    "journal": "Nature",
    "cite_key": "Yaeger2019",
    "evidence": "Neuromodulatory control of localized dendritic spiking in critical period cortex",
    "effect_size": "10 ms",
    "text_access": "fulltext",
    "study_system": "mouse V1",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 48,
    "claim_source_sentence": "To obtain a more informed understanding of how vision drives plasticity during critical periods and why this influence is lost with age, we investigated the modulation of pyramidal neurons and the three major types of inhibitory neurons in primary visual cortex: dendrite-targeting SST cells, soma-targeting PV cells, and cells expressing the vasoactive intestinal peptide (VIP) 18 .",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "In control studies in which SST cells expressed channelrhodopsin (ChR2), blue light pulses of 10 ms duration at 15 Hz reliably drove SST cell responses ( Extended Data Fig."
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": "10 ms",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-d2aa74034d77"
  ],
  "source_span": "To obtain a more informed understanding of how vision drives plasticity during critical periods and why this influence is lost with age, we investigated the modulation of pyramidal neurons and the three major types of inhibitory neurons in primary visual cortex: dendrite-targeting SST cells, soma-targeting PV cells, and cells expressing the vasoactive intestinal peptide (VIP) 18 .",
  "study_system": "mouse V1",
  "evidence_refs": [
    {
      "ref": "paper:paper-d2aa74034d77"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Neuromodulatory control of localized dendritic spiking in critical period cortex",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}