Version history

{
  "scope": "continuous bump-attractor model + macaque PFC physiology under cholinergic stimulation",
  "claim_text": "Increased neural excitability in a continuous bump-attractor model broadens neural tuning while decreasing bump diffusion, as long as firing rates are saturated; this can explain why cholinergic basal-forebrain stimulation improves performance despite widening prefrontal tuning.",
  "raw_fields": {
    "n": 2,
    "doi": "10.1523/jneurosci.1225-23.2024",
    "claim": "Increased neural excitability in a continuous bump-attractor model broadens neural tuning while decreasing bump diffusion, as long as firing rates are saturated; this can explain why cholinergic basal-forebrain stimulation improves performance despite widening prefrontal tuning.",
    "cite_key": "Mahrach2024",
    "evidence": "Continuous bump-attractor model of PFC fitted to two-monkey nucleus basalis stimulation working-memory data (Qi et al., 2021).",
    "effect_size": "qualitative",
    "text_access": "abstract_only",
    "study_system": "continuous bump-attractor model + macaque PFC physiology under cholinergic stimulation",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Here, we show that increased neural excitability in a simple continuous bump attractor model can induce broader neural tuning and decrease bump diffusion, provided neural rates are saturated.",
    "source_provenance_status": "non_substring_match",
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    "effect_size_source_sentence": null
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  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json",
  "effect_size": "qualitative",
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  "source_span": "Here, we show that increased neural excitability in a simple continuous bump attractor model can induce broader neural tuning and decrease bump diffusion, provided neural rates are saturated.",
  "study_system": "continuous bump-attractor model + macaque PFC physiology under cholinergic stimulation",
  "evidence_refs": [
    {
      "ref": "paper:paper-6bfbadb5788b"
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  "section_title": "13. Attractor-network models — Hopfield, ring, line, bump; what each model requires of the cortical E→E matrix and what the mouse empirical record provides",
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      "Local review repositories are read-only inputs.",
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    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
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  "evidence_summary": "Continuous bump-attractor model of PFC fitted to two-monkey nucleus basalis stimulation working-memory data (Qi et al., 2021).",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
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  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_13_evidence_package.json",
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}