Details

scope
unspecified
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
effect_size
4
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-06-synaptic-properties
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Fast-spiking parvalbumin-positive (PV) neurons provide precisely timed, context-dependent inhibition within cortical circuits.
study_system
unspecified
section_title
Synaptic Properties and Connectivity
evidence_summary
Reported in journal (2025); from Body of abstract.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-06-synaptic-properties
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing — Fast-spiking parvalbumin-positive (PV) neurons provide precisely timed, context-dependent inhibition within cortical circuits
raw_fields
{
  "n": 0,
  "doi": "10.1101/2025.11.06.686832",
  "claim": "A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing — Fast-spiking parvalbumin-positive (PV) neurons provide precisely timed, context-dependent inhibition within cortical circuits",
  "title": null,
  "cite_key": "Ganesh2025",
  "evidence": "Reported in journal (2025); from Body of abstract.",
  "effect_size": "4",
  "text_access": "abstract_only",
  "study_system": "unspecified",
  "_source_cluster": "cluster_05_synaptic_connectivity",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 300,
  "claim_source_sentence": "Fast-spiking parvalbumin-positive (PV) neurons provide precisely timed, context-dependent inhibition within cortical circuits.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Here, we identify the PV-specific silent voltage-gated potassium (Kv) channel subunit Kv6.4 (encoded by Kcng4 ), whose role in cortical PV neuron physiology was previously unknown, as a modulator of both intrinsic and synaptic properties."
}
source_refs
[
  "paper:8091c292-47f5-4c20-aea6-0c12060f42af"
]
evidence_refs
[
  {
    "ref": "paper:8091c292-47f5-4c20-aea6-0c12060f42af"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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