Details
- scope
- macaque dorsolateral prefrontal cortex, in vivo iontophoresis
- claim_text
- Beta1-adrenoceptor activation has mixed effects on PV fast-spiking interneurons in dlPFC during working memory tasks
- section_id
- section_06_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-06
- source_kind
- review_finding
- source_path
- evidence/section_06_evidence_package.json
- source_span
- Iontophoresis of a beta1-AR agonist had a mixed effect, increasing the firing of a subset and decreasing the firing of others, likely reflecting loss of firing of the entire microcircuit.
- study_system
- macaque dorsolateral prefrontal cortex, in vivo iontophoresis
- section_title
- Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
- evidence_summary
- Beta1-AR expressed on PV dendrites in primate dlPFC; beta1-AR antagonist nebivolol prevented stress-induced working memory deficits
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-06
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.ynstr.2024.100628", "claim": "Beta1-adrenoceptor activation has mixed effects on PV fast-spiking interneurons in dlPFC during working memory tasks", "evidence": "Beta1-AR expressed on PV dendrites in primate dlPFC; beta1-AR antagonist nebivolol prevented stress-induced working memory deficits", "effect_size": null, "text_access": "abstract_only", "study_system": "macaque dorsolateral prefrontal cortex, in vivo iontophoresis", "replication_status": "replication_unknown", "claim_source_sentence": "Iontophoresis of a beta1-AR agonist had a mixed effect, increasing the firing of a subset and decreasing the firing of others, likely reflecting loss of firing of the entire microcircuit.", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-fff3aaa31d0b" ]
- evidence_refs
[ { "ref": "paper:paper-fff3aaa31d0b" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }