Axo-axonic synapses innervate the entire length of the AIS rather than forming…

Details

scope: mouse piriform cortex, VGAT-ChR2-YFP mice
claim_text: Axo-axonic synapses innervate the entire length of the AIS rather than forming a concentrated cartridge, and EGABA at AIS is inhibitory (-73.6 mV)
section_id: section_04_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
effect_size: EGABA at AIS: -73.6 ± 1.2 mV; perisomatic EGABA: -72.8 ± 1.1 mV
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-04
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: AASs innervate the entire length of the AIS, as opposed to forming a highly concentrated cartridge.
study_system: mouse piriform cortex, VGAT-ChR2-YFP mice
section_title: Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond
evidence_summary: Axo-axonic synapses innervate the entire length of the AIS rather than forming a concentrated cartridge, and EGABA at AIS is inhibitory (-73.6 mV)
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: contested
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-04
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_04_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 12,
  "doi": "10.1113/jphysiol.2014.275719",
  "claim": "Axo-axonic synapses innervate the entire length of the AIS rather than forming a concentrated cartridge, and EGABA at AIS is inhibitory (-73.6 mV)",
  "evidence": "Axo-axonic synapses innervate the entire length of the AIS rather than forming a concentrated cartridge, and EGABA at AIS is inhibitory (-73.6 mV)",
  "effect_size": "EGABA at AIS: -73.6 ± 1.2 mV; perisomatic EGABA: -72.8 ± 1.1 mV",
  "text_access": "fulltext",
  "study_system": "mouse piriform cortex, VGAT-ChR2-YFP mice",
  "replication_status": "contested",
  "claim_source_sentence": "AASs innervate the entire length of the AIS, as opposed to forming a highly concentrated cartridge.",
  "replication_evidence_dois": [
    "10.3389/neuro.04.015.2009"
  ],
  "effect_size_source_sentence": "We found that the GABA reversal potential (EGABA) was -73.6 ± 1.2 mV when induced at the AIS and -72.8 ± 1.1 mV when induced at the perisomatic site."
}

source_refs

[
  "paper:paper-6bf445de772c"
]

evidence_refs

[
  {
    "ref": "paper:paper-6bf445de772c"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Axo-axonic synapses innervate the entire length of the AIS rather than forming…

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Replication

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