Details

scope
mammal S1/M1
claim_text
The activity of VIP interneurons increases during whisking Our results indicate that S1-projecting vM1 pyramidal neurons strongly recruit VIP interneurons in S1 superficial layers and that VIP interneurons preferentially inhibit SST cells.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
effect_size
100% of
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
source_span
The activity of VIP interneurons increases during whisking Our results indicate that S1-projecting vM1 pyramidal neurons strongly recruit VIP interneurons in S1 superficial layers and that VIP interneurons preferentially inhibit SST cells.
study_system
mammal S1/M1
section_title
Introduction
evidence_summary
A disinhibitory circuit mediates motor integration in the somatosensory cortex
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/nn.3544",
  "year": "2013",
  "claim": "The activity of VIP interneurons increases during whisking Our results indicate that S1-projecting vM1 pyramidal neurons strongly recruit VIP interneurons in S1 superficial layers and that VIP interneurons preferentially inhibit SST cells.",
  "title": null,
  "journal": "Nature neuroscience",
  "cite_key": "Lee2013",
  "evidence": "A disinhibitory circuit mediates motor integration in the somatosensory cortex",
  "effect_size": "100% of",
  "text_access": "fulltext",
  "first_author": "Lee",
  "study_system": "mammal S1/M1",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Lee, Kruglikov, Huang",
  "replication_status": "independently_replicated",
  "_source_cluster_index": 4,
  "claim_source_sentence": "The activity of VIP interneurons increases during whisking Our results indicate that S1-projecting vM1 pyramidal neurons strongly recruit VIP interneurons in S1 superficial layers and that VIP interneurons preferentially inhibit SST cells.",
  "replication_evidence_dois": [
    "10.1038/nn.3446",
    "10.1038/nature12676",
    "10.1016/j.cell.2014.01.050"
  ],
  "effect_size_source_sentence": "Together, 5HT3aR-, PV- and SST-expressing interneurons include close to 100% of supragranular interneurons 15 , 16 ."
}
source_refs
[
  "paper:paper-f02f24cb44ff"
]
evidence_refs
[
  {
    "ref": "paper:paper-f02f24cb44ff"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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