Details
- scope
- mouse postnatal cortex, P7-P40
- claim_text
- Kv3.1 (Kcnc1) and Kv3.2 (Kcnc2) channels are critical for the fast-spiking phenotype of PV interneurons, enabling rapid repolarization and high-frequency firing.
- section_id
- section_02_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- effect_size
- Kv3 channel upregulation between P10-P25 correlates with FS phenotype emergence
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-02
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- source_span
- upregulation of two-pore K+ leak channels between P10 and P25 contributes to one of the major differences between the intrinsic membrane properties of immature and adult FS cells.
- study_system
- mouse postnatal cortex, P7-P40
- section_title
- Molecular Identity and Transcriptomic Taxonomy
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-02
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/jneurosci.0105-09.2009", "claim": "Kv3.1 (Kcnc1) and Kv3.2 (Kcnc2) channels are critical for the fast-spiking phenotype of PV interneurons, enabling rapid repolarization and high-frequency firing.", "evidence": "", "effect_size": "Kv3 channel upregulation between P10-P25 correlates with FS phenotype emergence", "text_access": "abstract_only", "study_system": "mouse postnatal cortex, P7-P40", "replication_status": "independently_replicated", "claim_source_sentence": "upregulation of two-pore K+ leak channels between P10 and P25 contributes to one of the major differences between the intrinsic membrane properties of immature and adult FS cells.", "replication_evidence_dois": [ "10.1016/j.cell.2017.08.032" ], "effect_size_source_sentence": "upregulation of two-pore K+ leak channels between P10 and P25 contributes to one of the major differences between the intrinsic membrane properties of immature and adult FS cells" }- source_refs
[ "paper:paper-591943f1ad14" ]
- evidence_refs
[ { "ref": "paper:paper-591943f1ad14" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }