Details
- scope
- mouse motor cortex (M1), in vitro slice, retrograde labeling + LSPS
- claim_text
- In mouse motor cortex, sublayer-specific excitatory microcircuits target corticospinal vs corticostriatal L5 pyramidal neurons differently, defining distinct sources of cortical input to the two projection classes.
- section_id
- section_01
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- source_kind
- review_finding
- source_path
- evidence/section_01_evidence_package.json
- source_span
- Two projection classes centrally involved in motor control are corticospinal and corticostriatal neurons, as these represent the cortical origins of what are sometimes termed the 'pyramidal' and 'extrapyramidal' motor systems, respectively.
- study_system
- mouse motor cortex (M1), in vitro slice, retrograde labeling + LSPS
- section_title
- 1. Introduction — what "excitatory recurrence" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis
- evidence_summary
- Laser-scanning photostimulation glutamate uncaging onto retrogradely labeled corticospinal and corticostriatal L5 neurons in mouse motor-cortex slices.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-01-introduction
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/nn.2538", "claim": "In mouse motor cortex, sublayer-specific excitatory microcircuits target corticospinal vs corticostriatal L5 pyramidal neurons differently, defining distinct sources of cortical input to the two projection classes.", "cite_key": "Anderson2010", "evidence": "Laser-scanning photostimulation glutamate uncaging onto retrogradely labeled corticospinal and corticostriatal L5 neurons in mouse motor-cortex slices.", "effect_size": null, "text_access": "fulltext", "study_system": "mouse motor cortex (M1), in vitro slice, retrograde labeling + LSPS", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Two projection classes centrally involved in motor control are corticospinal and corticostriatal neurons, as these represent the cortical origins of what are sometimes termed the 'pyramidal' and 'extrapyramidal' motor systems, respectively.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-e4f11964cdc5" ]
- evidence_refs
[ { "ref": "paper:paper-e4f11964cdc5" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }