Details

scope
mouse V1 and PPC; two-photon calcium imaging during go/no-go visual discrimination before and after sensorimotor reversal
section_id
section_10
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json
effect_size
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-10-persistent-activity
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
source_span
Unlike V1 neurons, most PPC neurons reflect the animal's choice of the new target stimulus after re-training.
study_system
mouse V1 and PPC; two-photon calcium imaging during go/no-go visual discrimination before and after sensorimotor reversal
section_title
10. Physiological signature II — persistent activity and attractor dynamics supported by E→E recurrence (delay-period activity in mouse PFC/ALM, working memory, head-direction)
evidence_summary
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-10-persistent-activity
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Mouse posterior parietal cortex neurons respond largely only during task engagement and, after reversal of the sensorimotor contingency, predominantly track the animal's choice of the new target rather than the visual stimulus — unlike V1, where most neurons remain stimulus-locked — supporting a sensorimotor-transformation rather than purely sensory role for PPC.
raw_fields
{
  "n": 0,
  "doi": "10.1038/s41467-018-05012-y",
  "claim": "Mouse posterior parietal cortex neurons respond largely only during task engagement and, after reversal of the sensorimotor contingency, predominantly track the animal's choice of the new target rather than the visual stimulus — unlike V1, where most neurons remain stimulus-locked — supporting a sensorimotor-transformation rather than purely sensory role for PPC.",
  "cite_key": "Pho2018",
  "evidence": "",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "mouse V1 and PPC; two-photon calcium imaging during go/no-go visual discrimination before and after sensorimotor reversal",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Unlike V1 neurons, most PPC neurons reflect the animal's choice of the new target stimulus after re-training.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/nature10918",
    "10.1038/nn.4403"
  ],
  "effect_size_source_sentence": "Unlike V1 neurons, which respond robustly to stimuli in both conditions, most PPC neurons respond exclusively during task engagement."
}
source_refs
[
  "paper:paper-8a23b19ef4d4"
]
evidence_refs
[
  {
    "ref": "paper:paper-8a23b19ef4d4"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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