CCKBCs and PVBCs in the mPFC form both chemical synapses and gap junctions with…

Details

scope: mouse medial prefrontal cortex
claim_text: CCKBCs and PVBCs in the mPFC form both chemical synapses and gap junctions within their own cell type, and the two basket cell types are also interconnected
section_id: section_06_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
effect_size: The amplitude of uEPSCs in PVBCs received from local PNs did not decrease considerably and remained in the 80–106% range of the first uEPSC on average (second uEPSC: 106.65 ± 5.19% and fifth uEPSC: 78.2 ± 6.03%).
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-06
source_kind: review_finding
source_path: evidence/section_06_evidence_package.json
source_span: Basket cells form chemical synapses and gap junctions with their own cell type.
study_system: mouse medial prefrontal cortex
section_title: Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
evidence_summary: Paired recordings demonstrated both electrical and chemical synaptic connections within and between basket cell populations
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-06
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 35,
  "doi": "10.1113/jp286284",
  "claim": "CCKBCs and PVBCs in the mPFC form both chemical synapses and gap junctions within their own cell type, and the two basket cell types are also interconnected",
  "evidence": "Paired recordings demonstrated both electrical and chemical synaptic connections within and between basket cell populations",
  "effect_size": "The amplitude of uEPSCs in PVBCs received from local PNs did not decrease considerably and remained in the 80–106% range of the first uEPSC on average (second uEPSC: 106.65 ± 5.19% and fifth uEPSC: 78.2 ± 6.03%).",
  "text_access": "fulltext",
  "study_system": "mouse medial prefrontal cortex",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Basket cells form chemical synapses and gap junctions with their own cell type.",
  "replication_evidence_dois": [
    "10.1523/eneuro.0441-21.2022",
    "10.1152/jn.00071.2016"
  ],
  "effect_size_source_sentence": "The amplitude of uEPSCs in PVBCs received from local PNs did not decrease considerably and remained in the 80–106% range of the first uEPSC on average (second uEPSC: 106.65 ± 5.19% and fifth uEPSC: 78.2 ± 6.03%)."
}

source_refs

[
  "paper:paper-4d0daef43dfa"
]

evidence_refs

[
  {
    "ref": "paper:paper-4d0daef43dfa"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

CCKBCs and PVBCs in the mPFC form both chemical synapses and gap junctions with…

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Replication

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