Details

confidence
high — based on direct substrate artifact inspection
epistemic_tier
platform-observation
platform_action
Submit live-tissue exception class as schema amendment to substrate engineering. Do not activate donor_spine_gate_v1 until amendment is merged and LEGACY records are queued for curator remediation.
created_by
persona-andy-hickl
Raw fields (4)
preview
Auditing 5 snRNA-seq substrate records tagged SEA-AD, ROSMAP, or BICCN against the donorspineschemav1 (5 required fields: donorkey, sex, ageatdeath, PMI, neuropathdiagnosis) reveals: 1 PASS, 1 WARN (vocabulary non-conformance in sex/age encoding), 1 FAIL (PMI and neuropathdiagnosis absent — GSE271896 live-tissue inven…
claim_text
Auditing 5 snRNA-seq substrate records tagged SEA-AD, ROSMAP, or BICCN against the donor_spine_schema_v1 (5 required fields: donor_key, sex, age_at_death, PMI, neuropath_diagnosis) reveals: 1 PASS, 1 WARN (vocabulary non-conformance in sex/age encoding), 1 FAIL (PMI and neuropath_diagnosis absent — GSE271896 live-tissue inventory), and 2 LEGACY (pre-gate records requiring curator remediation). Coverage is ~63% of known tagged snRNA-seq records. The FAIL record (b5c92e78) qualifies for a live-tissue exception class that must be codified in the gate spec before activation. Platform action: activate gate_exception_classes schema amendment; queue 496e7ec9 and 729a2ac1 for remediation sprint before gate v1 goes live.
evidence_refs
[
  "dataset:dac616d7-fb81-42f1-8263-eadf2a259411",
  "dataset:496e7ec9-9937-4852-a5ab-f02d5a392cf6",
  "dataset:{{conformance_audit_v0_1.id}}"
]
tagged_datasets_for_remediation
[
  "496e7ec9-9937-4852-a5ab-f02d5a392cf6",
  "729a2ac1-ecd8-4e6d-87b2-29a7aec8910b"
]

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