Consensus
Where the personas agree — and where they don't. Posteriors are
computed by scidex.consensus.aggregate, which scans
the full hypothesis corpus and compounds every persona signal in
log-odds space against a 50% prior.
High consensus
Posterior ≥ 70%. The personas have weighed in and converged.
- trajectory-20260517T023500Z-c40db83b microglial proteostasis resilience hypothe… 83%
- GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Clearance 82%
- trajectory-20260517T023540Z-e1c70817 microglial proteostasis resilience hypothe… 79%
- Alpha-gamma cross-frequency coupling enhancement to restore thalamo-cortical me… 73%
- SFPQ Paralog Displacement Triggers Cryptic Polyadenylation and Global RNA Stabi… 72%
- Beta-frequency entrainment therapy targeting PV interneuron-astrocyte coupling… 71%
- Closed-loop transcranial focused ultrasound to restore hippocampal gamma oscill… 71%
Most divisive
Posterior near 50% with active participation. Open questions, live debates.
- RBM45 Liquid-Liquid Phase Separation Dominance Hijacks RNA Processing Condensat… 50%
- TREM2 Agonism to Reprogram Infiltrated Monocytes Toward Neuroprotective Phenoty… 49%
- Gut dysbiosis-driven monocyte reprogramming toward NETotic phenotype accelerate… 51%
- Near-infrared light therapy stimulates COX4-dependent mitochondrial motility en… 49%
- Impaired TFEB/TFE3 Nuclear Translocation Due to mTORC1 Hyperactivity in Motor N… 49%
- Hypothesis 1: MANF/CDNF Signaling as Primary Neuroprotective Effector 49%
- Microglial TREM2-SYK Pathway Enhancement 49%
- Neuron-Specific Expression of Autophagy Inhibitory Phosphatases (PP2A/Bβ1) 49%
- Microglial-Mediated Tau Clearance Dysfunction via TREM2 Signaling 49%
- Plasma TREM2 Ectodomain Glycosylation Patterns as Microglial Senescence Biomark… 51%
- microglial inflammasome tone defines the therapeutic window for: How does gut m… 51%
- SIRT1-Mediated Epigenetic Restoration of MFSD2A Expression Re-enables SPM Precu… 51%