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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Alpha-Synuclein Immunotherapy
α-Synuclein Pathology α-Synuclein is a 140-amino acid
Read more → - Neuroinflammation in Parkinson's Disease
α-Synuclein as Trigger:** - Oligomeric α-synuclein acts as DAMP
Read more → - Zombosomes — Anucleated Cell Couriers in Alpha-Synuclein Propagation
α-synuclein loading involves several steps: 1. **α-Synuclein uptake
Read more → - Cinumercept for Multiple System Atrophy (NCT04449485)
α-synuclein pathology through neural networks. Pathological α-synuclein can be released
Read more → - Astrocyte Dysfunction in Parkinson's Disease
α-synuclein in astrocytes - Megalin receptor contributes to α-synuclein
Read more →
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Related hypotheses
- Targeting Bacterial Curli Fibrils to Prevent α-Synuclein Cross-Seeding
Targeting Bacterial Curli Fibrils to Prevent α-Synuclein Cross-Seeding starts from the claim that ... characterized by the accumulation of misfolded α-synuclein aggregates, primar…
- Bacterial Curli Amyloid → Nucleation of α-Synuclein Misfolding in Enteric Neurons
bacterial curli amyloid fibers and human α-synuclein aggregates, which share common cross-β sheet ... structural motif found in pathological α-synuclein fibrils. At the molecular…
- Ferroptosis Inhibition for α-Synuclein Neuroprotection
conditions. The connection between ferroptosis and α-synuclein pathology involves multiple mechanistic links. α-Synuclein ... proteins and disrupting ferritin function. Pathologi…
- Autophagosome-Lysosome Fusion Defects as Primary Driver of α-Synuclein Propagation
serving as a primary driver of α-synuclein propagation in neurodegeneration. The molecular machinery governing ... creating a cellular environment conducive to α-synuclein aggrega…
- Bacterial Tyramine–Induced DOPAL Accumulation in Enteric Neurons
between gut microbiota, dopamine metabolism, and α-synuclein pathology in enteric neurons. Bacterial tyrosine decarboxylase ... with lysine and histidine residues on α-synuclein, …