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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Aduhelm
Aβ plaques | Aβ protofibrils | Aβ plaques | | Binding affinity | High (plaques
Read more → - Neuritic Amyloid Plaques — Histomorphologic Evidence of Pathologic Synergy in AD
Aβ plaques | Phase 3 | Approved | | CLARITY-AD | Lecanemab | Aβ plaques
Read more → - hyp_493636
Aβ Plaques → Enable/Accelerate Isocortical Spread ↓ Without Aβ: Tau limited to MTL (PART
Read more → - Anti-Amyloid Immunotherapy Comparison Matrix for Alzheimer's Disease
Aβ plaques. It binds to Aβ plaques and recruits microglia
Read more → - Neuritic Plaques
Aβ**: Ser8 phosphorylation has been detected in plaque-associated Aβ
Read more →
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Related hypotheses
- TREM2 Agonism to Restore Microglial Phagocytosis Across Both Pathologies
brain's capacity to clear both Aβ plaques and tau seeds. Small-molecule TREM2 agonists ... accumulation—TREM2 knockout mice show accelerated Aβ plaque formation, while selective T…
- Matrix Stiffness Normalization via Targeted Lysyl Oxidase Inhibition
reduction in cortical and hippocampal Aβ plaque burden, as quantified by thioflavin-S staining ... underlying disease processes. In 5xFAD mice, Aβ plaque burden remained 30-40% be…