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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- BDNF Signaling Pathway in Neurodegeneration
Bdnf_Signaling["Bdnf Signaling"] BDNF["BDNF"] ==>|"activates"| Bdnf_Signaling["Bdnf
Read more → - BDNF Neurons
BDNF) Neurons BDNF Neurons Name BDNF Neurons Type Cell Type
Read more → - Brain-Derived Neurotrophic Factor (BDNF)
BDNF ### Pro-BDNF vs Mature BDNF BDNF is initially synthesized
Read more → - BDNF Gene
BDNF["BDNF"] -->|"activates"| TRKB["TRKB"] BDNF["BDNF"] -->|"expressed in"| HIPPOCAMPUS
Read more → - BDNF/Neurotrophin Signaling in Neurodegeneration
BDNF Deficiency - **Reduced BDNF in substantia nigra**: Markedly decreased BDNF
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Related hypotheses
- Hippocampal CA3-CA1 synaptic rescue via DHHC2-mediated PSD95 palmitoylation stabilization
transmission in Alzheimer's disease (AD), with BDNF signaling as a key downstream effector ... NMDA receptor clustering and impairs synaptic transmission. BDNF signaling becomes c…
- Hippocampal CA3-CA1 circuit rescue via neurogenesis and synaptic preservation
preservation starts from the claim that modulating BDNF within the disease context of Alzheimer ... preservation, focusing on brain-derived neurotrophic factor (BDNF) upregulation…
- Epigenetic Memory Reprogramming for Alzheimer's Disease
Disease starts from the claim that modulating BDNF, CREB1, synaptic plasticity genes within the disease ... degraded. **Therapeutic Gene Targets for AD** 1. **BDNF upregulation (p…
- Neuroplasticity-Enhanced Learning Hypothesis
Hypothesis starts from the claim that modulating BDNF within the disease context of methodology ... Hypothesis starts from the claim that modulating BDNF within the disease contex…
- SASP Modulation Rather Than Cell Elimination
from the claim that modulating NFKB1,IL1B,BDNF within the disease context of neurodegeneration ... factors such as brain-derived neurotrophic factor (BDNF). --- ## Mechanistic Fr…