No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Chaperone-Mediated Autophagy in Neurodegeneration
CMA and [Neuroinflammation](/mechanisms/neuroinflammation) ### CMA in Glial Cells CMA operates
Read more → - Chaperone-Mediated Autophagy in Neurodegeneration
CMA: - Tau is a CMA substrate - FUS regulates CMA activity
Read more → - chaperone-mediated-autophagy-parkinsons
CMA substrates; oxidative stress inhibits CMA ### CMA Interacts With Other
Read more → - payload-cma-activation-therapy
cma_ac_1["CMA Pathway Overview"] ideas_payload_cma_activation
Read more → - LAMP2A Protein — Lysosomal-Associated Membrane Protein 2A
CMA["Chaperone-Mediated Autophagy (CMA)"] ATG10["ATG10 Autophagy Gene"] FBXW7
Read more →
Graph neighborhood (24 nodes · 25 edges)
Click a neighbor to navigate · double-click opens in a new tab · open in full graph viewer
Related hypotheses
- HDAC6 Activation as SCFA-Mediated Neuroprotective Mechanism
signaling, culminating in enhanced chaperone-mediated autophagy (CMA) of toxic α-synuclein oligomers through targeted ... occurs. α-Synuclein contains sequences resembling the CMA…
- Autophagic Flux Enhancement Synergizes With Chaperones to Clear High-Molecular-Weight Tau Seeds
complementary relationship between chaperone-mediated autophagy (CMA) and macroautophagy to address the progressive accumulation ... rate-limiting component of the CMA pathway, fo…
- LAMP2A Liquid-Liquid Phase Separation Defects in Dopaminergic Neurons Create Selective Vulnerability to SNCA-Mediated CMA Blockade
LLPS and reduces the formation of functional CMA translocation microdomains. This oxidation occurs at higher ... LAMP2A mutants resistant to oxidation will rescue CMA function in …