No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Enteric Neurons in Alzheimer's Disease
cognitive decline, with constipation being a particularly common early symptom
Read more → - Long-term Effects of Hearing Intervention on Brain Health in the Aging and Co... (NCT05532657)
Cognitive Decline** - **Mild Cognitive Impairment** - **Dementia** - **Hearing Loss** ## Scientific Background
Read more → - Vascular Risk Factors in Alzheimer's Disease
cognitive decline. **Epidemiological Evidence:** The Framingham Heart Study and other
Read more → - Cerebral Small Vessel Disease
cognitive decline in aging populations ([Pantoni, 2010](https://doi.org/10.1016/S1474-4422(10)70104-6)).
Read more → - DBS-fMRI Cognitive Decline Study (NCT06960096): Neural Basis for Cognitive Decline Following STN-DBS
Cognitive Decline Study NCT06960096: Ne"] clinical_trials_dbs_fmri_cogni
Read more →
Graph neighborhood (30 nodes · 46 edges)
Click a neighbor to navigate · double-click opens in a new tab · open in full graph viewer
Related hypotheses
- Microglial TREM2 downregulation impairs damage-associated response in late-stage Alzheimer's disease
tangles, accompanied by neuroinflammation and cognitive decline. Microglia, the resident immune cells of the central ... well-documented clinical progression of cognitive decline …
- Sphingomyelin Synthase Activators for Raft Remodeling
tricyclic antidepressants shows 20% slower cognitive decline compared to SSRI-treated controls, prompting prospective trial ... lecanemab achieves only 35% slowing of cognitive de…
- Microglial ACE Enhancement for Amyloid Clearance
complex neurodegenerative disorder characterized by progressive cognitive decline, with amyloid-β (Aβ) plaques serving ... with reduced dementia risk and slower cognitive decline,…
- OPC differentiation blockade contributes to white matter degeneration in early-stage AD
independent pathogenic process that contributes to cognitive decline through progressive myelin loss, compromised axonal energy ... vulnerability could explain variable presentati…
- Neutral Sphingomyelinase-2 Inhibition for Synaptic Protection in Neurodegeneration
ceramide accumulation preceding synaptic loss and cognitive decline. SMPD3 knockout mice exhibit enhanced synaptic plasticity ... neuronal death and correlating closely with cogni…