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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- FUS (Fused in Sarcoma) Protein
FUS["FUS"] RNA["RNA Processing"] FUS -->|"regulates"| RNA style FUS
Read more → - FUS Gene-Mechanism-Therapy Causal Chain — ALS/FTD
FUS-ALS | FUS-FTD | FTD-FUS | |---------|----------|---------|---------| | **Inclusions** | FUS-positive | FUS
Read more → - FUS — Fused in Sarcoma
FUS["FUS"] ALS["ALS"] -->|"associated with"| FUS["FUS"] RNA_oligonucleotides
Read more → - FUS Protein-Targeting Therapy for ALS/FTD
FUS["FUS"] ALS["ALS"] -->|"associated with"| FUS["FUS"] RNA_oligonucleotides
Read more → - FUS Mutations in Amyotrophic Lateral Sclerosis
FUS transgenic mice**: Express mutant FUS, reproduce key features - **FUS
Read more →
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Related hypotheses
- ASO-Mediated Exon Skipping to Restore FUS-TAZ Chaperone Axis
Overview ASO-Mediated Exon Skipping to Restore FUS-TAZ Chaperone Axis starts from the claim ... that modulating FUS within the disease context of neurodegeneration can redirect a …
- FUS Mutations Impede G3BP1's Chaperone Function, Exposing Neurotoxic Stress Granule Intermediates
Mechanistic Overview FUS Mutations Impede G3BP1's Chaperone Function, Exposing Neurotoxic Stress Granule Intermediates starts ... from the claim that modulating FUS within the dis…
- FUS Mutations Alter Stress Granule Material Properties to Confer Autophagy Resistance
liquid phase separation (LLPS) properties of mutant FUS proteins and their consequent resistance to autophagic ... clearance. FUS (Fused in Sarcoma) is an RNA-binding protein cont…
- FUS-ALS-Specific Ferroptosis Vulnerability Through NCOA4-Mediated Ferritinophagy Targeting
Mechanistic Overview FUS-ALS-Specific Ferroptosis Vulnerability Through NCOA4-Mediated Ferritinophagy Targeting starts from ... process. The original description reads: "## Mechan…
- Focused Ultrasound with Microbubble Contrast Agents for Antibody CNS Delivery
complexes to the actin cytoskeleton. Focused ultrasound (FUS) technology exploits acoustic cavitation phenomena to achieve ... five familial AD mutations. In these studies, FUS-me…