No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- huntington-disease-treatment
Huntington["Huntington"] HUNTINGTON["HUNTINGTON"] -->|"associated with"| Huntington["Huntington"] NEURODEGENERATIVE_DISEASES
Read more → - Huntington's Study Group (HSG)
Huntington's Study Group (HSG) The **Huntington's Study Group
Read more → - Cholinergic Interneurons in Huntington Disease
Huntington["Huntington"] HUNTINGTON["HUNTINGTON"] -->|"associated with"| Huntington["Huntington"] NEURODEGENERATIVE_DISEASES
Read more → - Huntington's Disease
Huntington's Disease ## Huntington's Disease ## Pathway / Mechanism Diagram ```mermaid
Read more → - Huntingtin (HTT)
Huntington's Disease (Primary) HTT mutations cause Huntington's disease
Read more →
Graph neighborhood (30 nodes · 37 edges)
Click a neighbor to navigate · double-click opens in a new tab · open in full graph viewer
Related hypotheses
- Trinucleotide Repeat Sequestration via CRISPR-Guided RNA Targeting
pathological RNA gain-of-function mechanisms driving Huntington's disease, myotonic dystrophy, and fragile ... most devastating neurodegenerative conditions, such as Huntington's …
- PDE10A Inhibition to Bypass RGS6 Deficiency via cAMP Pathway Normalization
Pfizer) advanced to Phase II trials for Huntington's disease and showed trends toward improved ... Therapeutics) was developed for Huntington's disease and showed good tolerabilit…
- Metabolic Reprogramming Toward GAPDH Inhibition
Alzheimer's disease, Parkinson's disease, Huntington's disease, and ALS, GAPDH aggregation, oxidative modification ... trapping GAPDH in the cytoplasm. In Huntington's disease: Mu…
- Isoform-Selective Hsp70 Targeting Overcomes Stoichiometric Imbalance in Advanced Pathology
protein aggregates in Alzheimer's, Parkinson's, Huntington's, and ALS represent massive molecular reservoirs ... failed Phase III but demonstrated target engagement), Huntington's…
- Temporal CAG Repeat Stabilization via CRISPR-Mediated DNA Mismatch Repair Modulation
hypothesis addresses the fundamental molecular mechanism underlying Huntington's disease and certain ALS/FTD syndromes ... onset and progression in polyglutamine diseases. In Hunt…