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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Lipid Peroxidation in Neurodegeneration
lipid_peroxidation["lipid_peroxidation"] -->|"causes"| ferroptosis["ferroptosis"] LIPID_PEROXIDATION["LIPID
Read more → - Lipid Peroxidation in Neurodegeneration
Lipid Peroxidation in Neurodegeneration ## Overview Lipid peroxidation is a chain
Read more → - Ferroptosis in Neurodegeneration
Peroxidation"] end subgraph Lipid_Peroxidation["Lipid Peroxidation Pathway"] H --> I["AA/AdA
Read more → - Ferroptosis in Alzheimer's Disease
lipid_peroxidation["lipid_peroxidation"] -->|"causes"| ferroptosis["ferroptosis"] autophagy["autophagy"] -->|"regulates
Read more → - Ferroptosis Hypothesis in Parkinson's Disease
lipid peroxidation: - **Iron requirement**: Ferrous iron (Fe²⁺) catalyzes lipid peroxidation
Read more →
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Related hypotheses
- Senescence-Induced Lipid Peroxidation Spreading
Mechanistic Overview Senescence-Induced Lipid Peroxidation Spreading starts from the claim that modulating GPX4/SLC7A11 within ... mediated by iron dysregulation and lipid peroxid…
- Ferroptosis as Primary Driver of Motor Neuron Death
peroxidase 4 (GPX4) inactivation, and resulting lipid peroxidation representing the decisive molecular cascade that irreversible ... iron-dependent accumulation of lipid peroxides…
- ACSL4-Driven Ferroptotic Priming in Disease-Associated Microglia
primary substrates for iron-catalyzed lipid peroxidation—the biochemical hallmark of ferroptosis [PMID ... membranes—removes the critical defense against lipid peroxidation [PMID:…
- Ferroptosis Inhibition for α-Synuclein Neuroprotection
cell death characterized by iron-dependent lipid peroxidation and subsequent membrane damage, fundamentally different from ... provides the catalytic metal necessary for lipid per…
- Sequential Iron Chelation (Deferoxamine) and GPX4 Restoration (Sulforaphane) Prevents the Self-Amplifying Iron-Ferroptosis-Edema Cascade Post-Cardiac Arrest
pathological cascade centered on iron-mediated lipid peroxidation and ferroptosis, ultimately preventing the devastating neurological ... cell death driven by iron-dependent lipid…