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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- MAPK/ERK Signaling Pathway in Neurodegeneration
MAPK AKT -->|"regulates"| MAPK MTOR -->|"regulates"| MAPK ERK -->|"activates"| MAPK
Read more → - MAPK Signaling Inhibitors: Investment Landscape Analysis
Mapk["Mapk"] OPTN["OPTN"] -->|"interacts with"| Mapk["Mapk"] DNM1L["DNM1L
Read more → - MAPK Signaling Pathways in Neurodegeneration
Mapk["Mapk"] PI3K["PI3K"] -->|"regulates"| Mapk["Mapk"] AKT["AKT"] -->|"associated
Read more → - neflamapimod-psp
MAPK Signaling Pathway **p38 mitogen-activated protein kinase (p38 MAPK
Read more → - JNK/p38 MAPK Signaling Pathway in Neurodegeneration
MAPK signaling cascades[@activates2020]. **Key mechanisms of Aβ-induced MAPK
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Related hypotheses
- DLK MAPK Pathway Inhibition to Block Tau-Induced Neurotoxicity Without Directly Targeting Tau
Mechanistic Overview DLK MAPK Pathway Inhibition to Block Tau-Induced Neurotoxicity Without Directly Targeting ... relevant process. The original description reads: "# DLK MAPK Pa…
- Astrocyte CD38-erk Mapk signaling controls mitochondrial transfer to neurons via Tnt-mediated vesicle trafficking
stress, astrocytes upregulate CD38, which triggers Erk MAPK signaling to promote tunneling nanotube (TNT) formation
- Astrocyte-Intrinsic NLRP3 Inflammasome Activation by Alpha-Synuclein Aggregates Drives Non-Cell-Autonomous Neurodegeneration
hyperphosphorylation through activation of neuronal p38 MAPK and GSK-3β signaling, creating a mechanistic link ... plasma - Drives tau phosphorylation via p38-MAPK and activates a…
- Peripheral-to-Central Inflammation Circuit Breaker
mitogen-activated protein kinase (MAPK) pathways, ultimately leading to transcription of additional inflammatory mediators ... IL1R1 and IL1R2, activating NF-kB and MAPK pathways.…
- IL-6 Trans-Signaling Blockade at the Oligodendrocyte-Microglia Interface
production. This signaling also activates the MAPK pathway through ERK1/2 and p38 phosphorylation, further amplifying ... gp130 signaling and downstream JAK-STAT and MAPK pathways…