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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Tanycyte-Mediated Protein Clearance Therapy for Neurodegeneration
protein clearance | | Root-Cause Coverage | 8 | Addresses impaired protein clearance
Read more → - Protein Clearance Mechanisms
Protein Clearance Mechanisms in Neurodegeneration ## Overview **Protein clearance mechanisms** are essential
Read more → - CCNF Protein
Protein Quality Control**: Clearance of damaged or misfolded proteins - **Transcriptional
Read more → - LRP10 Protein
protein clearance Strategy Status **Gene therapy** Research **Protein clearance modulators
Read more → - SCRIB Gene
Protein Clearance and Autophagy SCRIB is involved in protein clearance
Read more →
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- Conditional CRISPR Kill Switches for Aberrant Protein Clearance
Conditional CRISPR Kill Switches for Aberrant Protein Clearance starts from the claim that modulating UBE3A ... Conditional CRISPR Kill Switches for Aberrant Protein Clearance sta…
- Osmotic Gradient Restoration via Selective AQP1 Enhancement in Choroid Plexus
suggesting reduced neuronal injury and improved protein clearance. These biomarker changes precede and predict subsequent ... other neurodegenerative conditions characterized by i…
- Early Proteasome Restoration Therapy
rapamycin or trehalose to activate complementary protein clearance pathways. Safety considerations for PSMC restoration therapy ... interpreted as beneficial microglial activatio…
- TRPML1-PINK1/Parkin Axis Coordinates Mitophagy with Lysosomal Biogenesis
lysosomal dysfunction. MCOLN1 activation promotes clearance of protein aggregates. - **Datasets:** Allen Human Brain Atlas, GTEx ... TRPML1 agonist (ML-SA1) promotes clearance of …
- Sequential TRPML1 Activation Following Autophagy Priming
demonstrated that TRPML1 agonists promote clearance of protein aggregates including α-synuclein and mutant huntingtin ... impaired lysosomal function leading to defective protein …