remap_tfbs read
scidex.forge.remap_tfbs
Query ReMap (remap.univ-amu.fr) for transcription factor binding peaks from ChIP-seq, ChIP-exo, and DAP-seq experiments. ReMap2022 covers human, mouse, Drosophila, and Arabidopsis. Two query modes: 'tf_symbol' to find all peaks for a TF (e.g. 'FOXA1'), or 'region' to find all peaks overlapping a genomic region (e.g. 'chr8:127000000-127001000'). Input: tf_symbol or region (mutually exclusive), genome (default 'hg38'), limit (default 20). Output: peaks with tf_name, chrom, start (0-based), end, experiment, cell_type, score; not_found flag; source attribution. Free API, no auth required. API: https://remap.univ-amu.fr/
Invoke
Calls scidex.tool.invoke on the substrate with
this tool name. Edit the JSON below — it must match the
input schema. The substrate runs the tool, records the call
in substrate_tool_calls, and returns a
structured envelope.
Sign in to invoke this tool. Schema and curl snippet are visible to anyone.
Schemas
Input schema
{
"additionalProperties": false,
"description": "Input schema for ``scidex.forge.remap_tfbs``.",
"properties": {
"tf_symbol": {
"anyOf": [
{
"type": "string"
},
{
"type": "null"
}
],
"default": null,
"description": "Transcription factor gene symbol to query (e.g. 'FOXA1', 'CTCF'). Either ``tf_symbol`` or ``region`` must be provided, but not both. Case-insensitive; will be uppercased for the API call.",
"title": "Tf Symbol"
},
"region": {
"anyOf": [
{
"type": "string"
},
{
"type": "null"
}
],
"default": null,
"description": "Genomic region in ``chr:start-end`` format (e.g. ``'chr8:127000000-127001000'``). Either ``tf_symbol`` or ``region`` must be provided, but not both. 1-based coordinates are converted to 0-based internally.",
"title": "Region"
},
"genome": {
"default": "hg38",
"description": "Reference genome assembly. Default ``'hg38'`` (Homo sapiens). Also accepts ``'hg19'``, ``'mm10'``, ``'mm39'``, ``'dm6'`` (Drosophila), ``'at'`` (Arabidopsis).",
"title": "Genome",
"type": "string"
},
"limit": {
"default": 20,
"description": "Maximum number of peak records to return. Default 20.",
"maximum": 500,
"minimum": 1,
"title": "Limit",
"type": "integer"
}
},
"title": "ForgeRemapTfbsIn",
"type": "object"
}Output schema
{
"$defs": {
"RemapPeak": {
"description": "One ReMap TF ChIP-seq binding peak record.",
"properties": {
"tf_name": {
"description": "Gene symbol of the transcription factor (e.g. 'FOXA1').",
"title": "Tf Name",
"type": "string"
},
"chrom": {
"description": "Chromosome (e.g. 'chr8').",
"title": "Chrom",
"type": "string"
},
"start": {
"description": "0-based genomic start coordinate.",
"title": "Start",
"type": "integer"
},
"end": {
"description": "Genomic end coordinate (exclusive).",
"title": "End",
"type": "integer"
},
"experiment": {
"description": "Experiment identifier (e.g. ENCSR accession) or 'unknown'.",
"title": "Experiment",
"type": "string"
},
"cell_type": {
"default": "unknown",
"description": "Cell type or tissue of the ChIP-seq experiment.",
"title": "Cell Type",
"type": "string"
},
"score": {
"default": 0,
"description": "Peak score (higher = more significant). 0.0 when not reported.",
"title": "Score",
"type": "number"
}
},
"required": [
"tf_name",
"chrom",
"start",
"end",
"experiment"
],
"title": "RemapPeak",
"type": "object"
}
},
"description": "Response shape for ``scidex.forge.remap_tfbs``.",
"properties": {
"query": {
"description": "The query that was made: either the TF symbol or the genomic region.",
"title": "Query",
"type": "string"
},
"query_mode": {
"description": "Query mode used: 'tf_symbol' or 'region'.",
"title": "Query Mode",
"type": "string"
},
"peaks": {
"description": "ReMap TF binding peaks matching the query, capped at ``limit``. Sorted by score descending (highest score first).",
"items": {
"$ref": "#/$defs/RemapPeak"
},
"title": "Peaks",
"type": "array"
},
"not_found": {
"default": false,
"description": "True when no peaks were found for the given query.",
"title": "Not Found",
"type": "boolean"
},
"source": {
"default": "ReMap (remap.univ-amu.fr)",
"description": "Data source attribution.",
"title": "Source",
"type": "string"
}
},
"required": [
"query",
"query_mode"
],
"title": "ForgeRemapTfbsOut",
"type": "object"
}curl snippet
Replace $SCIDEX_JWT with a valid bearer token. Read
verbs are usually accessible without auth in dev; production
requires a JWT.
curl -sS -X POST '/api/scidex/forge/remap_tfbs' \
-H 'authorization: Bearer $SCIDEX_JWT' \
-H 'content-type: application/json' \
-d '{}'Discussion
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