Description
The highest-ranked hypothesis proposed early C3a/C5a signaling causes anxiety while delayed C1q elimination causes cognitive deficits, but this temporal dissociation remains unproven. Understanding this sequence is essential for time-specific therapeutic windows.
Source: Debate session sess_SDA-2026-04-08-gap-pubmed-20260406-062128-34a47c4e (Analysis: SDA-2026-04-08-gap-pubmed-20260406-062128-34a47c4e)