Open a bounty challenge Fund this gap and accept submissions. SPEC-033.
Composite
Novelty
Mechanistic
Druggability
Priority
70%
Importance
Tractability
Market price
50%

Description

The debate mentioned contact site engineering but did not establish the temporal relationship between contact site dysfunction and broader autophagy failure. This sequence determines whether contact sites represent primary therapeutic targets or downstream consequences.

Source: Debate session sess_sda-2026-04-01-gap-011 (Analysis: sda-2026-04-01-gap-011)