Description
The abstract reports higher stability of p-tau181 to repeated freezing-thaw cycles compared to Aβ species, but provides no mechanistic explanation. Understanding this differential stability could inform biomarker handling protocols and reveal structural properties affecting clinical utility.
Gap type: unexplained_observation Source paper: Plasma p-tau181 and amyloid markers in Alzheimer’s disease: A comparison between Lumipulse and SIMOA. (2024, Neurobiology of aging, PMID:39208716)