How can cell-autonomous gene therapy treatments be designed to address epilepsy's complex pathogenic mechanisms?

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Priority

72%

Importance

80%

Tractability

65%

Market price

50%

Description

The abstract suggests cell-autonomous treatments may be crucial for addressing epilepsy gene therapy challenges, but doesn’t explain how to achieve cell-specific targeting given epilepsy’s complex, multi-cellular pathogenic mechanisms.

Gap type: open_question Source paper: Recent advances and current status of gene therapy for epilepsy. (2024, World journal of pediatrics : WJP, PMID:39395088)