Description
The study reveals a striking contradiction where FB1 decreases ceramide content by half in lungs but increases it 3.5-fold in liver. This tissue-specific paradox suggests unknown regulatory mechanisms that could be critical for understanding organ-selective toxicity.
Gap type: unexplained_observation Source paper: New insights into the organ-specific adverse effects of fumonisin B1: comparison between lung and liver. (2015, Archives of toxicology, PMID:25155190)