Description
SYNCRIP binds to C2B domains of most synaptotagmins except Syt-V, -VI, and -X, but the functional consequences of this selective interaction pattern remain unknown. Understanding this selectivity could reveal distinct regulatory mechanisms for different synaptotagmin isoforms in membrane trafficking and exocytosis.
Gap type: unexplained_observation Source paper: SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms. (None, None, PMID:10734137)