Description
Western blot revealed significant vAChT reduction (-27.2%) while immunocytochemistry showed no change in vAChT-positive terminal numbers. This methodological discrepancy suggests either technical artifacts or different aspects of cholinergic terminal pathology that need clarification.
Gap type: contradiction Source paper: Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer’s disease. (None, None, PMID:24029236)