Description
The abstract describes that AETA causes conformational modifications of GluN1 subunits that favor non-ionotropic signaling, but the specific molecular interactions and structural changes are not explained. Understanding this mechanism is crucial for developing targeted therapeutics for NMDAR-related disorders.
Gap type: unexplained_observation Source paper: APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors. (None, None, PMID:38878768)