Description
The abstract reveals AETA’s unique dual regulatory capacity but doesn’t explain what factors control this bidirectional switch between signaling modes. This mechanistic understanding is essential for predicting AETA’s effects in different physiological and pathological contexts.
Gap type: unexplained_observation Source paper: APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors. (None, None, PMID:38878768)