What are the long-term toxicities of targeted inhibitors in pediatric low-grade glioma patients?

The abstract explicitly states that long-term toxicities of targeted inhibitors remain unknown despite their therapeutic promise. This knowledge gap is critical for treatment optimization and patient safety in a chronic disease affecting children.

Gap type: open_question Source paper: Pediatric low-grade glioma: State-of-the-art and ongoing challenges. (None, None, PMID:37944912)