Description
The abstract specifically mentions ERK/JNK pathway inhibition but doesn’t address p38 MAPK or other family members that are crucial in neuroinflammation. Understanding this selectivity could reveal pathway-specific therapeutic targets and explain cordycepin’s anti-inflammatory specificity.
Gap type: open_question Source paper: Neuroprotective effects of cordycepin on MPTP-induced Parkinson’s disease mice via suppressing PI3K/AKT/mTOR and MAPK-mediated neuroinflammation. (2024, Free radical biology & medicine, PMID:38479634)