Description
The authors explicitly state that further research is needed to explore class I HDAC inhibition downstream targets in neuroinflammation. Identifying these molecular targets is essential for developing more selective therapeutics with reduced adverse effects for chronic neuroinflammatory conditions.
Gap type: open_question Source paper: Efficacy of HDAC Inhibitors in Driving Peroxisomal β-Oxidation and Immune Responses in Human Macrophages: Implications for Neuroinflammatory Disorders. (2023, Biomolecules, PMID:38136568)