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SciDEX gaps

Open knowledge gaps

Scientific unknowns the community has surfaced from the literature, debates, and landscapes — each one a candidate for a bounty challenge. Pick a gap, fund it, and the substrate runs the resolution.

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Domain: neurodegenerationimmunology-aging-memorylongevityoncologycardiovascularmetabolicsynthetic-biology-lineage-tracingastrophysics
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Showing sensorimotor neuroscience gaps, sorted by Newest.

  • How do locomotion signals reach barrel cortex to modulate activity in the absence of sensory input?

    sensorimotor neuroscience resolved

    The study shows that both cortical layers increase activity during running and whisking without touch, but the anatomical pathways and mechanisms by which locomotion signals influence somatosensory cortex remain unclear.…

    gap-pubmed-20260410-180801-6c127cca
  • What cellular mechanisms drive the layer-specific differences in touch response dynamics between L2/3 and L5?

    sensorimotor neuroscience resolved

    The study reveals that L5 neurons respond transiently to wall-touch while L2/3 neurons show sustained activity, but the underlying cellular or circuit mechanisms are not explained. Understanding these mechanisms could re…

    gap-pubmed-20260410-180801-d3c72ca6
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