Do CTD phosphatase inhibitors selectively reduce dilncRNA synthesis without global transcriptional toxicity?

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Description

The skeptic raised critical concerns about selectivity of CTD phosphatase modulation, noting potential for global transcriptional arrest. The temporal and spatial specificity of this approach at DSB sites versus normal genes is unresolved.

Source: Debate session sess_SDA-2026-04-08-gap-pubmed-20260406-062229-35a642ca (Analysis: SDA-2026-04-08-gap-pubmed-20260406-062229-35a642ca)

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