How do small molecules partition into and modulate the composition of pathological protein condensates?

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Description

The drug delivery hypothesis assumed molecules could selectively partition into condensates, but no evidence exists for this mechanism. Understanding condensate-drug interactions is critical for developing condensate-targeted therapeutics.

Source: Debate session sess_SDA-2026-04-08-gap-pubmed-20260406-062229-3ab00c95 (Analysis: SDA-2026-04-08-gap-pubmed-20260406-062229-3ab00c95)

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