What are the temporal dynamics of SPI1 activity during microglial state transitions in cerebrovascular disease?

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Description

The debate proposed temporal SPI1 inhibition strategies but lacked data on when and how long SPI1 drives pathological versus beneficial microglial functions. Understanding these dynamics is essential for therapeutic timing.

Source: Debate session sess_SDA-2026-04-08-gap-pubmed-20260406-062122-bfac06c8 (Analysis: SDA-2026-04-08-gap-pubmed-20260406-062122-bfac06c8)

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