What is the causal relationship between AQP4 mislocalization and tau strain-specific pathology patterns?

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Description

The debate presented correlative evidence but the Skeptic emphasized lack of causation data. Whether AQP4 disruption drives strain-specific spreading or results from it remains unresolved, limiting therapeutic targeting strategies.

Source: Debate session sess_SDA-2026-04-01-gap-005 (Analysis: SDA-2026-04-01-gap-005)

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