How do stress granules mechanistically amplify inflammatory signals between microglia and astrocytes?

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Description

The phase-separated organelle hypothesis identified stress granules as potential signal amplifiers, but the specific RNA-protein complexes and signaling cascades involved are unknown. Understanding this could enable precision targeting of G3BP1/2 pathways.

Source: Debate session sess_SDA-2026-04-01-gap-009 (Analysis: SDA-2026-04-01-gap-009)

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