Can cell-type specific circadian disruption selectively reduce neuroinflammatory crosstalk without systemic effects?

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Description

The feasibility assessment raised concerns about targeting CLOCK/BMAL1 without disrupting essential circadian functions. The therapeutic window for selective inflammatory modulation versus global circadian disruption remains unexplored.

Source: Debate session sess_SDA-2026-04-01-gap-009 (Analysis: SDA-2026-04-01-gap-009)

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