What biomarkers can stratify ALS patients most likely to respond to ferroptosis-targeted therapies?

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Description

The debate emphasized that iron chelation and other anti-ferroptosis approaches may only benefit specific patient subsets, but no validated stratification strategy exists. This represents a critical barrier to successful clinical translation of ferroptosis-based therapeutics.

Source: Debate session ds-SDA-2026-04-16-gap-ferroptosis-als-d2fb6bf796ed (Analysis: SDA-2026-04-16-gap-ferroptosis-als-d2fb6bf796ed)

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