What drives presynaptic glycosyltransferase dysregulation in early AD pathogenesis?

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Description

The debate assumed altered glycosyltransferase expression causes SV protein hypoglycosylation but did not identify upstream mechanisms. Understanding whether amyloid, tau, or other factors drive this change is critical for intervention timing.

Source: Debate session sess_SDA-2026-04-16-gap-debate-20260411-065018-92a34465_20260416-134725 (Analysis: SDA-2026-04-16-gap-debate-20260411-065018-92a34465)

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