CD4/Tfh Help and Germinal-center Memory in Older Adults

immunology-aging-memory open composite 52%
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Composite
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Description

Map whether defective help, altered lymphoid niches, or B-cell intrinsic aging is the dominant bottleneck in durable memory generation. Boundary domains: humoral-immunity, vaccinology. Representative papers: CD4 T cell defects in the aged: causes, consequences and strategies to circumvent.; How T follicular helper cells and the germinal centre response change with age.

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