Human Intervention Trials Targeting Immune-memory Aging

immunology-aging-memory open composite 71%
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Composite
71%
Novelty
86%
Mechanistic
—
Druggability
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Priority
71%
Importance
84%
Tractability
73%
Market price
50%

Description

The field lacks intervention trials with matched cellular-memory readouts that can separate rejuvenation from transient immune activation. Boundary domains: clinical-immunology, geroscience. Representative papers: Immune Checkpoint Inhibitors in the Aged.; Does patient age influence anti-cancer immunity?; Cancer Immunotherapies: Are They as Effective in the Elderly?

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    "include_provenance": true,
    "actions": [
      "signal_fund",
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      "open_bounty_challenge"
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}